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KMID : 0359919950140010147
Korean Journal of Nephrology
1995 Volume.14 No. 1 p.147 ~ p.151
A Case of Antiphospholipid Antibody Syndrome Associated with Recurrent Cerebral Infarcts in Lupus Nephritis


Abstract
The antiphospholipid antibody syndrome is now a well-recognized novel disorder and it is charac-terized clinically by arterial or venous thrombosis, thrombocytopenia, recurrent fetal wastage, and liv-edo reticularis-one that can be diagnosed from
the
clinical history and special laboratory test.
We have experienced a typical case of anti-phospholipid antibody syndrome in lupus nephritis as-sociated with recurrent cerebral thromboses in the presence of high trter antrcardiolipin antibody and positive lupus anticoagulant test.
The patient is 28 years-old woman with systemic lupus erythematosus, with was diagnosed in anoth-er hospital 3 years ago. Renal biopsy had proved to be diffuse proliferative lupus nephritis. She had three attacks of stroke in recent three years.
The
patient is well treated by steroid pulse therapy and immediate heparinization, followed by maintenance oral steroid and watarin therapy.
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